Halide Functional group transformation

Halide Functional group transformation lists all halide involved transformation to help students while the organic synthesis of molecules. Malonic ester synthesis The alkylation of malonic ester enolates with various organic halides and the subsequent decarboxylation of the alkylated products to yield substituted acetic acid derivatives. organic halides here is 1° and 2° alkyl halides and […]

Carboxylic acid Functional Group Transformation

Functional Group Transformation of Carboxylic acid is listed here for students’ help. This collection helps students in retrosynthesis and synthesis of organic molecules. Passerini multicomponent reaction Isocyanides react with carboxylic acids and carbonyl compounds to provide α-acyloxycarboxamides. Hell-Volhard-Zelinsky reaction Preparation of α-halo carboxylic acids by treating a carboxylic acid with halogen at elevated temperatures in […]

ENONE Functional Group Transformation

Functional Group Transformation of ENONE is listed here for students’ help. This collection helps students in retrosynthesis and synthesis of organic molecules. Wacker oxidation α,β-unsaturated ketones and esters are oxidized regioselectively to 1,3-Dicarbonyl compounds using catalytic amounts of Na2PdCl4 and TBHP or H2O2 as co-oxidants Stetter reaction The addition of aliphatic and aromatic aldehydes across […]